Dr. Keith G. Andrews

Biography

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Keith Andrews received his MChem from Imperial College London, including a 13 month industrial placement at GlaxoSmithKline, Stevenage, where he worked with a breakout PROTAC (proteolysis targeting chimera) development team collaborating with Prof. Craig Crews. During his MChem project with Prof. Alan Spivey, he developed a computational approach to remove systematic error in Density Functional Theory (DFT) NMR shift predictions, allowing ambiguous configurational isomers to be distinguished in a total synthesis project.

He moved to start his PhD with Ross Denton at the University of Nottingham in 2013, where he developed an organocatalytic Mitsunobu reaction for the inversion of secondary alcohols, and new reductive amination methodologies using hydridosilanes, including a three-component reductive-amination-trifluoroethylation protocol. He also developed an interest in using kinetic analysis for mechanistic investigations.

In 2018, Keith moved to the University of Oxford for post-doctoral research with Prof. Harry Anderson FRS to learn supramolecular chemistry, templating, and host-guest recognition techniques. Here he worked on supramolecular porphyrin arrays, the synthesis of single molecule magnets, and the development of novel conjugated organic pi-systems.

In 2019, he was awarded a Royal Commission 1851 Research Fellowship to begin independent work on low molecular weight enzyme mimics for catalysis and molecular recognition, hosted in the lab of Harry Anderson, and joined Linacre College as an EPA Research Fellow.

In 2023 he moved to Durham to start his research group.